Budget Impact Analysis of Warfarin Reversal Therapies Among Hip Fracture Patients in Finland

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Budget Impact Analysis of Warfarin Reversal Therapies Among Hip Fracture Patients in Finland

BACKGROUND Hip fractures require operation within 36-48 h, and they are most common in the elderly. A high International Normalized Ratio should be corrected before surgery. In the current study, we analyzed the budget impact of various warfarin reversal approaches. METHODS Four reversal strategies were chosen for the budget impact analysis: the temporary withholding of warfarin, administrati...

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Warfarin therapy and risk of hip fracture among elderly patients.

STUDY OBJECTIVE To ascertain the relationship between warfarin therapy and subsequent hip fracture in a large elderly population. DESIGN Retrospective, population-based cohort study. SETTING Population-based health care administrative databases for Ontario, Canada. PATIENTS Elderly patients receiving warfarin (52,701 patients), thyroid replacement therapy (40,555), an oral corticosteroid ...

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Preoperative warfarin reversal for early hip fracture surgery.

PURPOSE To evaluate our hospital protocol of low-dose vitamin K titration for preoperative warfarin reversal for early hip fracture surgery. METHODS Records of 16 men and 33 women aged 63 to 93 (mean, 81) years who were taking warfarin for atrial fibrillation (n=40), venous thromboembolism (n=9), cerebrovascular accident (n=3), and prosthetic heart valve (n=3) and underwent surgery for hip fr...

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Comparison of different warfarin reversal protocols on surgical delay and complication rate in hip fracture patients.

PURPOSE. To compare the effects of different warfarin reversal protocols on surgical delay and complication rate in hip fracture patients. METHODS. Records of 7 men and 17 women aged 68 to 93 (mean, 82) years who were on warfarin and underwent surgery for femoral neck fractures were reviewed. The time to surgery, complication rate, and mortality were recorded, as were the International Normalis...

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Treatment with vitamin K in hip fracture patients receiving warfarin.

BACKGROUND Hip fractures are common in the elderly population, but surgical treatment of these fractures within the first 48 hours decreases morbidity and mortality. The management of patients with hip fracture requiring surgery who are taking warfarin anticoagulation is unclear. OBJECTIVES To determine the effect of vitamin K on hip fracture patients treated with warfarin. METHODS We retro...

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ژورنال

عنوان ژورنال: Drugs in R&D

سال: 2015

ISSN: 1174-5886,1179-6901

DOI: 10.1007/s40268-015-0088-6